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PSA, Screening

Test Summary

In men over 50 years with total PSA between 4.0 and 10.0 ng/mL, the percent (%) free PSA gives an estimate of the probability of cancer. In these circumstances the measurement of the % free PSA may aid in avoiding unnecessary biopsies.

Elevated levels of Prostate Specific Antigen (PSA) have been associated with benign and malignant prostatic disorders. Studies indicate that in men 50 years or older measurement of PSA is a useful addition to the digital rectal exam in the early detection of prostate cancer. In addition, PSA decreases to undetectable levels following complete resection of the tumor and may rise again with recurrent disease or persist with residual disease. Thus, PSA levels may be of assistance in the management of prostate cancer patients.

Aliases

  • Prostate Specific Antigen

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

1 mL

Instructions

Barrier tubes (serum separator tubes or plasma separator tubes) are preferred. If non-barrier tubes are utilized, the serum/plasma must be removed immediately after centrifuging and placed in a screw-cap transfer tube.

Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.

Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.

Patient Preparation

N/A

Storage

Original tube preferred, may be sent in a screw-top transfer tube

Transport Temperature

Room Temperature or Refrigerated

Specimen Stability

  • Room Temperature = 5 days
  • Refrigerated = serum 5 days
  • Frozen = 24 weeks

Limitations

N/A

Other Acceptable Specimens

Plasma from Lithium Heparin (Light Green Top) tube

Unacceptable Specimens

Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, contaminated sample.

Order Code

PSAS

EPIC (Premier) Code

LAB696

Includes

N/A

CPT Code

  • 84153

Billing Code

  • 300359

CPT Statement

CPT Statement

Methodology

Immunoassay (IA)

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine OH, 45439

Department

Chemistry

Reference Range

  • Males: <4.0 ng/mL
  • Female: <0.1 ng/mL

Setup Schedule / Expected Turnaround Time

24/7; Report available: Daily

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

1 mL

Instructions

Barrier tubes (serum separator tubes or plasma separator tubes) are preferred. If non-barrier tubes are utilized, the serum/plasma must be removed immediately after centrifuging and placed in a screw-cap transfer tube.

Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.

Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.

Patient Preparation

N/A

Storage

Original tube preferred, may be sent in a screw-top transfer tube

Transport Temperature

Room Temperature or Refrigerated

Specimen Stability

  • Room Temperature = 5 days
  • Refrigerated = serum 5 days
  • Frozen = 24 weeks

Limitations

N/A

Other Acceptable Specimens

Plasma from Lithium Heparin (Light Green Top) tube

Unacceptable Specimens

Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, contaminated sample.

Billing

CPT Code

  • 84153

Billing Code

  • 300359

CPT Statement

CPT Statement

Result Information

Methodology

Immunoassay (IA)

Testing Laboratory

N/A

Reference Range

  • Males: <4.0 ng/mL
  • Female: <0.1 ng/mL

Setup Schedule / Expected Turnaround Time

24/7; Report available: Daily