Methemoglobin
Test Summary
The iron in hemoglobin is normally maintained in the ferrous state by several effective mechanisms so that only a small percentage of the total hemoglobin is in the form of methemoglobin. The production of methemoglobin by oxidation of the iron to the ferric state, renders the hemoglobin incapable of interacting reversibly with molecular oxygen. The oxygen affinity of the unaffected heme is also increased, resulting in the decreased release of oxygen to the tissues at low partial pressure of oxygen. Methemoglobinemia is usually caused by exposure to various chemical agents, many which contain nitrogen.
Aliases
- Methgb
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL whole blood Sodium Heparin (dark green top) tube.
Minimum Volume
1 mL
Instructions
After specimen collected invert tubes 8 - 10 times, then transport tube on wet ice slurry to MVH or MVH South laboratory within 2 hours.
Patient Preparation
N/A
Storage
Lithium or Sodium Heparin (dark green top) tube
Transport Temperature
Transport on ice slurry to laboratory within 2 hours of collection.
Specimen Stability
- Room Temperature = 30 minutes
- Refrigerated = 2 hours on ice slurry
- Frozen = n/a
Limitations
N/A
Other Acceptable Specimens
Lithium Heparin (Light Green Top) tube
Unacceptable Specimens
Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.
Order Code
MHGB
EPIC (Premier) Code
LAB298
Includes
N/A
CPT Code
- 83050
Billing Code
- 300267
CPT Statement
Methodology
Ion Selective Electrode (ISE)
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine OH, 45439
2308 Sandridge Drive
Moraine OH, 45439
Department
Chemistry
Reference Range
See Report
Setup Schedule / Expected Turnaround Time
24/7; Report available: 2 hours from receipt
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL whole blood Sodium Heparin (dark green top) tube.
Minimum Volume
1 mL
Instructions
After specimen collected invert tubes 8 - 10 times, then transport tube on wet ice slurry to MVH or MVH South laboratory within 2 hours.
Patient Preparation
N/A
Storage
Lithium or Sodium Heparin (dark green top) tube
Transport Temperature
Transport on ice slurry to laboratory within 2 hours of collection.
Specimen Stability
- Room Temperature = 30 minutes
- Refrigerated = 2 hours on ice slurry
- Frozen = n/a
Limitations
N/A
Other Acceptable Specimens
Lithium Heparin (Light Green Top) tube
Unacceptable Specimens
Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.
Result Information
Methodology
Ion Selective Electrode (ISE)
Testing Laboratory
N/A
Reference Range
See Report
Setup Schedule / Expected Turnaround Time
24/7; Report available: 2 hours from receipt