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Carcinoembryonic Antigen, CEA

Test Summary

Increased serum CEA levels have been detected in persons with primary colorectal cancer and in patients with other malignancies involving the gastrointestinal tract, breast, lung, ovarian, prostatic, liver and pancreatic cancers. Elevated serum CEA levels have also been detected in patients with nonmalignant disease, especially patients who are older or who are smokers. CEA levels are not useful in screening the general population for undetected cancers. However, CEA levels provide important information about patient prognosis, recurrence of tumors after surgical removal, and effectiveness of therapy.

Aliases

  • CEA
  • Carcinoembryonic
  • CEA (serum)
  • CEA Level

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

1 mL

Instructions

Barrier tubes. If non-barrier tubes are utilized, the serum must be removed immediately after centrifuging and placed in a screw-cap transfer tube.

Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.

Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.

Patient Preparation

N/A

Storage

Original tube preferred, may be sent in a screw-top transfer tube.

Transport Temperature

Room Temperature or Refrigerated

Specimen Stability

  • Room temperature = 7 days
  • Refrigerated = 14 days
  • Frozen = 6 months

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.

Order Code

CEA2

EPIC (Premier) Code

LAB6858

Includes

N/A

CPT Code

  • 82378

Billing Code

  • 500336

CPT Statement

Methodology

Immunoassay (IA)

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine OH, 45439

Department

Chemistry

Reference Range

  • Non-Smoker: <2.5 U/mL
  • Smoker: <5.0 U/mL

Setup Schedule / Expected Turnaround Time

24/7; Report available: Daily

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

1 mL

Instructions

Barrier tubes. If non-barrier tubes are utilized, the serum must be removed immediately after centrifuging and placed in a screw-cap transfer tube.

Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.

Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.

Patient Preparation

N/A

Storage

Original tube preferred, may be sent in a screw-top transfer tube.

Transport Temperature

Room Temperature or Refrigerated

Specimen Stability

  • Room temperature = 7 days
  • Refrigerated = 14 days
  • Frozen = 6 months

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.

Billing

CPT Code

  • 82378

Billing Code

  • 500336

CPT Statement

Result Information

Methodology

Immunoassay (IA)

Testing Laboratory

N/A

Reference Range

  • Non-Smoker: <2.5 U/mL
  • Smoker: <5.0 U/mL

Setup Schedule / Expected Turnaround Time

24/7; Report available: Daily