FISH, Mantle Cell Lymphoma
Test Summary
This test is performed to detect the IGH-CCND1 fusion, translocation t(11;14) by FISH (fluorescence in situ hybridization). This assay is useful for diagnosis of mantle cell lymphoma and, risk assessment for plasma cell myeloma.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL whole blood or 3 mL bone marrow collected in sodium heparin (green-top) tube, or
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue
Minimum Volume
1 mL whole blood or bone marrow • 5x5 mm tissue
Instructions
3-5 mL whole blood or 1-3 mL bone marrow collected in a sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Limitations
N/A
Other Acceptable Specimens
Whole blood or bone marrow collected in: Sodium heparin (royal blue-top) or sodium heparin lead-free (tan-top) tube
Unacceptable Specimens
N/A
Order Code
MANTLE
EPIC (Premier) Code
LAB3278
Includes
N/A
CPT Code
- 88271(2)
- 88275
Billing Code
- 671076
- 671077
CPT Statement
Methodology
Fluorescence in situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
Interpretive report
Setup Schedule / Expected Turnaround Time
Daily; Report available: 5 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL whole blood or 3 mL bone marrow collected in sodium heparin (green-top) tube, or
5x5 mm fresh tissue collected in culture transport media or sterile container with Hanks' or Ringers solution, or
Tissue in Formalin-fixed paraffin-embedded tissue
Minimum Volume
1 mL whole blood or bone marrow • 5x5 mm tissue
Instructions
3-5 mL whole blood or 1-3 mL bone marrow collected in a sodium heparin tube, 5x5 mm Fresh tissue in sterile container, Formalin Fixed Paraffin Embedded Tissue
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Limitations
N/A
Other Acceptable Specimens
Whole blood or bone marrow collected in: Sodium heparin (royal blue-top) or sodium heparin lead-free (tan-top) tube
Unacceptable Specimens
N/A
Result Information
Methodology
Fluorescence in situ Hybridization (FISH)
Testing Laboratory
N/A
Reference Range
Interpretive report
Setup Schedule / Expected Turnaround Time
Daily; Report available: 5 days