Vanillymandelic Acid, 24 HR Urine w/o Creatinine
Order Code:
24UVMA
Test Summary
Vanillylmandelic Acid (VMA) is the major urinary project resulting from the metabolic degradation of catecholamine, norepinephrine and epinephrine. Elevated concentrations of VMA are commonly found in cases of catecholamine secreting tumors such as pheochromocytoma, neuroblastoma, and ganglioneuroma. Drugs which can interfere with testing due to physiologic response: clonidine, L-dopa, methocarbamol, monoamine oxidase inhibitors, reserpine, salicylates.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
10 mL aliquot from a 24-hour urine preserved with 25 mL 6N HCl, collected in a plastic, 24-hour urine container
Minimum Volume
5 mL
Instructions
Collect 24-hour urine with 25 mL 6N HCL to maintain a pH < or = 3. If no preservative is used, specimen must be stored refrigerated during collection but shipped frozen and pH must be < or = 6
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Preserved urine: Room temperature
Unpreserved urine: Frozen
Specimen Stability
Preserved urine:
- Room temperature: 10 days
- Refrigerated: 14 days
- Frozen: 1 year
Unpreserved urine:
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
Aliquot from a 24-hour urine, unpreserved, with a pH ≤6, collected in a plastic, 24-hour urine container
Unacceptable Specimens
Preserved urine received refrigerated with pH >3 • Unpreserved urine received frozen with pH >6
Order Code
24UVMA
EPIC (Premier) Code
LAB411
Includes
N/A
CPT Code
- 84585
- 81050
Billing Code
- 670501
- 500002
CPT Statement
Methodology
High Performance Liquid Chromatography (HPLC) • Electrochemical Detection
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
<3 Years Not established
3-8 Years ≤2.3 mg/24 h
9-12 Years ≤3.4 mg/24 h
13-17 Years ≤3.9 mg/24 h
Adult ≤6.0 mg/24 h
Setup Schedule / Expected Turnaround Time
Sunday-Friday; Report Available: 2 - 6 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
10 mL aliquot from a 24-hour urine preserved with 25 mL 6N HCl, collected in a plastic, 24-hour urine container
Minimum Volume
5 mL
Instructions
Collect 24-hour urine with 25 mL 6N HCL to maintain a pH < or = 3. If no preservative is used, specimen must be stored refrigerated during collection but shipped frozen and pH must be < or = 6
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Preserved urine: Room temperature
Unpreserved urine: Frozen
Specimen Stability
Preserved urine:
- Room temperature: 10 days
- Refrigerated: 14 days
- Frozen: 1 year
Unpreserved urine:
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
Aliquot from a 24-hour urine, unpreserved, with a pH ≤6, collected in a plastic, 24-hour urine container
Unacceptable Specimens
Preserved urine received refrigerated with pH >3 • Unpreserved urine received frozen with pH >6
Result Information
Methodology
High Performance Liquid Chromatography (HPLC) • Electrochemical Detection
Testing Laboratory
N/A
Reference Range
<3 Years Not established
3-8 Years ≤2.3 mg/24 h
9-12 Years ≤3.4 mg/24 h
13-17 Years ≤3.9 mg/24 h
Adult ≤6.0 mg/24 h
Setup Schedule / Expected Turnaround Time
Sunday-Friday; Report Available: 2 - 6 days