Yo Antibody Screen with Reflex to Titer and Western Blot, CSF
Test Summary
Purkinje Cell (Yo) antibody is found in approximately half of the patients with paraneoplastic cerebellar degeneration and is associated with ovarian, uterine, and small cell lung carcinomas and Hodgkin’s lymphoma.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.8 mL CSF
Minimum Volume
0.5 mL
Instructions
N/A
Patient Preparation
Overnight fasting is preferred
Storage
Sterile screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 8 hours
- Refrigerated: 7 days
- Frozen: 6 months
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received room temperature
Order Code
YOABCF
EPIC (Premier) Code
LAB5726
Includes
If Yo Antibody Screen, IFA, CSF is positive, Yo Antibody, Western Blot, CSF will be performed at an additional charge (CPT code(s): 84181).
If Yo Antibody, Western Blot, CSF is positive, Yo Antibody, Titer, CSF will be performed at an additional charge (CPT code(s): 86256).
If Yo Antibody, Western Blot, CSF is positive, Yo Antibody, Titer, CSF will be performed at an additional charge (CPT code(s): 86256).
CPT Code
- 86255
Billing Code
- 670780
CPT Statement
Methodology
Immunofluorescence Assay (IFA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
| Yo Ab Screen, IFA, CSF | Negative |
| Yo Ab, WB, CSF | Negative |
| Yo Ab, Titer, CSF | No Yo Antibodies detected in undiluted CSF sample |
Setup Schedule / Expected Turnaround Time
Monday, Wednesday, Friday morning; Report available: 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.8 mL CSF
Minimum Volume
0.5 mL
Instructions
N/A
Patient Preparation
Overnight fasting is preferred
Storage
Sterile screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 8 hours
- Refrigerated: 7 days
- Frozen: 6 months
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received room temperature
Result Information
Methodology
Immunofluorescence Assay (IFA)
Testing Laboratory
N/A
Reference Range
| Yo Ab Screen, IFA, CSF | Negative |
| Yo Ab, WB, CSF | Negative |
| Yo Ab, Titer, CSF | No Yo Antibodies detected in undiluted CSF sample |
Setup Schedule / Expected Turnaround Time
Monday, Wednesday, Friday morning; Report available: 4 days