Y Chromosome Microdeletion, DNA Analysis
Order Code:
YCHROM
Test Summary
To detect Y chromosome microdeletions associated with oligospermia and azoospermia. About 15-20% of azoospermic men and about 10% of severely oligospermic men present with microdeletions of Yq. This test targets 20 genetic loci, including those recommended by the European Quality Monitoring Network Group (Int J Andr 22:292-299 (1999).
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
3 mL
Instructions
Specimen type: Whole blood, lavender-top preferred. Specimen stability is crucial. Store and ship ambient immediately. Do not freeze.
Extracted DNA: Please call 1-866-GENE-INFO for additional information.
Extracted DNA: Please call 1-866-GENE-INFO for additional information.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 8 days
- Refrigerated: 8 days
- Frozen: Unacceptable
Limitations
This assay is limited to the detection of deletions that affect the markers listed above. We are unable to determine if the absence of a single marker is caused by a deletion or a nucleotide sequence variation in the binding site for one of the PCR primers used to amplify that marker. Although rare, false positive or false negative results may occur. All results should be interpreted in the context of clinical findings, relevant history, and other laboratory data.
Other Acceptable Specimens
Whole blood collected in: ACD (yellow-top)
Unacceptable Specimens
N/A
Order Code
YCHROM
EPIC (Premier) Code
LAB3190
Includes
N/A
CPT Code
- 81403
Billing Code
- 670862
CPT Statement
Methodology
Agarose Gel Electrophoresis • Polymerase Chain Reaction (PCR)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday, Wednesday, Friday; Report available: 4 - 5 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
3 mL
Instructions
Specimen type: Whole blood, lavender-top preferred. Specimen stability is crucial. Store and ship ambient immediately. Do not freeze.
Extracted DNA: Please call 1-866-GENE-INFO for additional information.
Extracted DNA: Please call 1-866-GENE-INFO for additional information.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 8 days
- Refrigerated: 8 days
- Frozen: Unacceptable
Limitations
This assay is limited to the detection of deletions that affect the markers listed above. We are unable to determine if the absence of a single marker is caused by a deletion or a nucleotide sequence variation in the binding site for one of the PCR primers used to amplify that marker. Although rare, false positive or false negative results may occur. All results should be interpreted in the context of clinical findings, relevant history, and other laboratory data.
Other Acceptable Specimens
Whole blood collected in: ACD (yellow-top)
Unacceptable Specimens
N/A
Result Information
Methodology
Agarose Gel Electrophoresis • Polymerase Chain Reaction (PCR)
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday, Wednesday, Friday; Report available: 4 - 5 days