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Tropheryma whipplei DNA Qualitative, Real-Time PCR

Test Summary

Tropheryma whipplei (Whipple's disease) DNA,  PCR is a highly sensitive and specific method to detect the presence of Tropheryma whipplei DNA in clinical specimens. The diagnosis of Tropheryma whipplei infection should not rely solely upon the result of a PCR assay. A positive result should be considered in conjunction with clinical presentation and additional established clinical tests. Moreover, this assay cannot differentiate between viable and nonviable organisms. A negative PCR result indicates the absence of Tropheryma whipplei DNA at detectable levels in the samples tested and does not exclude the diagnosis of disease.

Aliases

  • Whipple's Disease

Specimen Collection

Special Instructions

N/A

Preferred Specimen

> 3 mm3 biopsy, submitted in a sterile, plastic leak-proof container, or
0.7 mL CSF collected in a sterile, plastic leak-proof container, or
0.7 mL whole blood collected in an EDTA (lavender-top) tube, or ACD solution B (yellow-top) tube

Minimum Volume

3 mm3 frozen tissue • 0.3 mL CSF or whole blood

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Biopsy: Frozen
CSF and whole blood: Refrigerated (cold packs)

Specimen Stability

  • Biopsy and CSF
  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: 30 days
  • Whole blood
  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: Unacceptable

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

N/A

Order Code

TWHPQL

EPIC (Premier) Code

LAB3157

Includes

N/A

CPT Code

  • 87798 - This test is for non-New York patient testing. For New York patient testing on tissue samples
  • see test code 900262.

Billing Code

  • 700000

CPT Statement

Methodology

Real-Time Polymerase Chain Reaction (RT-PCR)

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Reference Range

Not detected

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 2 - 3 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

> 3 mm3 biopsy, submitted in a sterile, plastic leak-proof container, or
0.7 mL CSF collected in a sterile, plastic leak-proof container, or
0.7 mL whole blood collected in an EDTA (lavender-top) tube, or ACD solution B (yellow-top) tube

Minimum Volume

3 mm3 frozen tissue • 0.3 mL CSF or whole blood

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Biopsy: Frozen
CSF and whole blood: Refrigerated (cold packs)

Specimen Stability

  • Biopsy and CSF
  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: 30 days
  • Whole blood
  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: Unacceptable

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

N/A

Billing

CPT Code

  • 87798 - This test is for non-New York patient testing. For New York patient testing on tissue samples
  • see test code 900262.

Billing Code

  • 700000

CPT Statement

Result Information

Methodology

Real-Time Polymerase Chain Reaction (RT-PCR)

Testing Laboratory

N/A

Reference Range

Not detected

Setup Schedule / Expected Turnaround Time

Monday - Saturday; Report available: 2 - 3 days