TSH with HAMA Treatment
Test Summary
Precision in the estimation of TSH is crucial to the follow-up of subjects with thyroid disorders. The preincubation of samples to remove HAMA immunoglobulins provides a way to ensure that an otherwise unsuspected rise or drop in TSH concentration will not be interpreted as either a false positive or false negative.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum
Minimum Volume
1.5 mL
Instructions
N/A
Patient Preparation
Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks. According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra Assay."
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 7 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Order Code
TSHHMA
EPIC (Premier) Code
LAB5860
Includes
Ultrasensitive TSH with and without HAMA treatment
CPT Code
- 84443 (x2)
Billing Code
- 670746
CPT Statement
Methodology
Immunoassay (IA)
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
| TSH, HAMA Treated | See below |
| TSH, Untreated | |
| Premature infant (28-36 weeks), 1st week of life | 0.20-27.90 mIU/L |
| Term infant (>37 Weeks), serum or cord blood | 1.00-39.00 mIU/L |
| 1-2 Days | 3.20-34.60 mIU/L |
| 3-4 Days | 0.7-15.40 mIU/L |
| 5 Days-4 Weeks | 1.70-9.10 mIU/L |
| 1-11 Months | 0.80-8.20 mIU/L |
| 1-19 Years | 0.50-4.30 mIU/L |
| ≥20 Years | 0.40-4.50 mIU/L |
| Pregnancy | |
| First Trimester | 0.26-2.66 mIU/L |
| Second Trimester | 0.55-2.73 mIU/L |
| Third Trimester | 0.43-2.91 mIU/L |
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday; Report available: 2 - 3 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum
Minimum Volume
1.5 mL
Instructions
N/A
Patient Preparation
Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks. According to the assay manufacturer Siemens: "Samples containing fluorescein can produce falsely depressed values when tested with the Advia Centaur TSH3 Ultra Assay."
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 7 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Result Information
Methodology
Immunoassay (IA)
Testing Laboratory
N/A
Reference Range
| TSH, HAMA Treated | See below |
| TSH, Untreated | |
| Premature infant (28-36 weeks), 1st week of life | 0.20-27.90 mIU/L |
| Term infant (>37 Weeks), serum or cord blood | 1.00-39.00 mIU/L |
| 1-2 Days | 3.20-34.60 mIU/L |
| 3-4 Days | 0.7-15.40 mIU/L |
| 5 Days-4 Weeks | 1.70-9.10 mIU/L |
| 1-11 Months | 0.80-8.20 mIU/L |
| 1-19 Years | 0.50-4.30 mIU/L |
| ≥20 Years | 0.40-4.50 mIU/L |
| Pregnancy | |
| First Trimester | 0.26-2.66 mIU/L |
| Second Trimester | 0.55-2.73 mIU/L |
| Third Trimester | 0.43-2.91 mIU/L |
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday; Report available: 2 - 3 days