Chromosome Analysis, Tissue with Reflex to Microarray, ClariSure® Oligo-SNP
Test Summary
Chromosome analysis of products of conception (POC) can detect fetal chromosome abnormalities that are associated with approximately one-half of all first trimester spontaneous abortions. Since chromosome analysis on products of conception has an increased failure rate, this test will reflex to chromosomal microarray if chromosome analysis fails. Chromosomal microarray (CMA) detects aneuploidies, deletions and duplications below the resolution of chromosome analysis (karyotyping), and long continuous regions of homozygosity.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5x5 mm tissue collected in a sterile container in Hanks', Ringer's solution or culture medium with antibiotics
Minimum Volume
2x3 mm
Instructions
Tissue sample minimum 2x3 mm in culture medium with antibiotics or in a sterile container with Hanks', Ringer's or saline solution.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: Preferred
- Refrigerated: Acceptable
- Frozen: Unacceptable
- Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Order Code
TISCHR
EPIC (Premier) Code
LAB5271
Includes
If Chromosome Analysis result is "Tissue has no growth", then Chromosomal Microarray, POC, ClariSure® Oligo-SNP will be performed at an additional charge (CPT code(s): 81229).
CPT Code
- 88233
- 88262
Billing Code
- 670720
- 670719
CPT Statement
Methodology
Culture • Karyotype • Microscopy
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Chromosome reports 14 days/Micro-array 10 days if needed
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5x5 mm tissue collected in a sterile container in Hanks', Ringer's solution or culture medium with antibiotics
Minimum Volume
2x3 mm
Instructions
Tissue sample minimum 2x3 mm in culture medium with antibiotics or in a sterile container with Hanks', Ringer's or saline solution.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: Preferred
- Refrigerated: Acceptable
- Frozen: Unacceptable
- Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Result Information
Methodology
Culture • Karyotype • Microscopy
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Chromosome reports 14 days/Micro-array 10 days if needed