Thyroglobulin, Fine Needle Aspirate
Order Code:
THGFNA
Test Summary
Clinically enlarged cervical lymph nodes with a history of thyroid cancer are usually assessed by fine-needle aspiration biopsy (FNAB) followed by a cytology. Thyroglobulin (Tg) is frequently elevated in malignant FNAB needle wash specimens and it's use may possibly augment or replace cytology.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL fine needle aspirate (FNA) or thyroid-tissue washings submitted in a sterile transport tube
Minimum Volume
0.8 mL
Instructions
A 25-gauge needle is inserted obliquely within the transducer plane of view and moved back and forth (passes) through the nodule to compensate for patient movement and needle deflection. There is no suction device; cells move into the needle via capillary action. After collection of the cytology samples, withdraw between 0.10 and 0.25 mL of saline up through each needle and empty this fluid back through the needle into a tube. This is the needle washing used for analysis. Repeat the passes and saline washings from the same biopsied site and empty contents into the same tube. The washes from all needles are pooled (final volume 1 mL). Inspect specimen for visible blood or tissue contamination. If bloody, centrifuge specimen and transfer supernatant to a new tube to send to the laboratory. The supernatant, not the cellular materials, is used for analysis. If the specimen is clear, centrifugation is not necessary.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 14 days
- Refrigerated: 7 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
Non-lymph node • Non-nodal soft tissue • Cervical node washings
Unacceptable Specimens
Glass tubes
Order Code
THGFNA
EPIC (Premier) Code
LAB5982
Includes
N/A
CPT Code
- 84432
Billing Code
- 670714
CPT Statement
Methodology
Beckman Coulter Chemiluminescent
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
| Negative | ≤1.0 ng/mL |
| Indeterminate | 1.1-10.0 ng/mL |
| Consistent with thyroid tissue or metastatic thyroid cancer | >10.0 ng/mL |
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Saturday; Report available: 4 - 7 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL fine needle aspirate (FNA) or thyroid-tissue washings submitted in a sterile transport tube
Minimum Volume
0.8 mL
Instructions
A 25-gauge needle is inserted obliquely within the transducer plane of view and moved back and forth (passes) through the nodule to compensate for patient movement and needle deflection. There is no suction device; cells move into the needle via capillary action. After collection of the cytology samples, withdraw between 0.10 and 0.25 mL of saline up through each needle and empty this fluid back through the needle into a tube. This is the needle washing used for analysis. Repeat the passes and saline washings from the same biopsied site and empty contents into the same tube. The washes from all needles are pooled (final volume 1 mL). Inspect specimen for visible blood or tissue contamination. If bloody, centrifuge specimen and transfer supernatant to a new tube to send to the laboratory. The supernatant, not the cellular materials, is used for analysis. If the specimen is clear, centrifugation is not necessary.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 14 days
- Refrigerated: 7 days
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
Non-lymph node • Non-nodal soft tissue • Cervical node washings
Unacceptable Specimens
Glass tubes
Result Information
Methodology
Beckman Coulter Chemiluminescent
Testing Laboratory
N/A
Reference Range
| Negative | ≤1.0 ng/mL |
| Indeterminate | 1.1-10.0 ng/mL |
| Consistent with thyroid tissue or metastatic thyroid cancer | >10.0 ng/mL |
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Saturday; Report available: 4 - 7 days