Serotonin, Serum
Test Summary
Serotonin concentrations are greatly increased in patients with carcinoid syndrome. Carcinoid tumors are associated with Multiple Endocrine Neoplasia (MEN) Types I and II. These tumors are associated with flushing, diarrhea, pain, and other symptoms.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL frozen serum
Minimum Volume
1 mL
Instructions
Spin and freeze serum below -20° C within 2 hours after collection.
Patient Preparation
Patient should avoid foods high in indoles: avocado, banana, tomato, plum, walnut, pineapple, and eggplant. Patient should also avoid tobacco, tea, and coffee for 3 days before specimen collection.
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 42 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received refrigerated • Received room temperature
Order Code
SEROTS
EPIC (Premier) Code
LAB3381
Includes
N/A
CPT Code
- 84260
Billing Code
- 670474
CPT Statement
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
56-244 ng/mL
Setup Schedule / Expected Turnaround Time
Monday - Friday; Report available: 4 - 6 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL frozen serum
Minimum Volume
1 mL
Instructions
Spin and freeze serum below -20° C within 2 hours after collection.
Patient Preparation
Patient should avoid foods high in indoles: avocado, banana, tomato, plum, walnut, pineapple, and eggplant. Patient should also avoid tobacco, tea, and coffee for 3 days before specimen collection.
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: Unacceptable
- Frozen: 42 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received refrigerated • Received room temperature
Result Information
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Testing Laboratory
N/A
Reference Range
56-244 ng/mL
Setup Schedule / Expected Turnaround Time
Monday - Friday; Report available: 4 - 6 days