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Rituxan Sensitivity (CD20)

Test Summary

CD20 antigen is expressed on the surface of >90% of B-cell Non-Hodgkin's Lymphomas (NHL). Binding to CD20 antigen is necessary for the antitumor effect of Rituxan®.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

5 mL whole blood or bone marrow collected in a sodium heparin (green-top) tube or EDTA (lavender-top) tube or ACD solution B (yellow-top) tube

Minimum Volume

1 mL

Instructions

N/A

Patient Preparation

N/A

Storage

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 72 hours
  • Refrigerated: Unacceptable
  • Frozen: Unacceptable

Limitations

N/A

Other Acceptable Specimens

5 mL buffy coat or fresh (unfixed) tissue • CSF or tissue biopsy or fluid or pleural fluid

Unacceptable Specimens

Clotted or fixed sample

Order Code

RITUXN

EPIC (Premier) Code

LAB6159

Includes

N/A

CPT Code

  • 86356

Billing Code

  • 700000

CPT Statement

Methodology

Flow Cytometry (FC)

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Daily; Report available: 2 - 3 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

5 mL whole blood or bone marrow collected in a sodium heparin (green-top) tube or EDTA (lavender-top) tube or ACD solution B (yellow-top) tube

Minimum Volume

1 mL

Instructions

N/A

Patient Preparation

N/A

Storage

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 72 hours
  • Refrigerated: Unacceptable
  • Frozen: Unacceptable

Limitations

N/A

Other Acceptable Specimens

5 mL buffy coat or fresh (unfixed) tissue • CSF or tissue biopsy or fluid or pleural fluid

Unacceptable Specimens

Clotted or fixed sample

Billing

CPT Code

  • 86356

Billing Code

  • 700000

CPT Statement

Result Information

Methodology

Flow Cytometry (FC)

Testing Laboratory

N/A

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Daily; Report available: 2 - 3 days