Rituxan Sensitivity (CD20)
Test Summary
CD20 antigen is expressed on the surface of >90% of B-cell Non-Hodgkin's Lymphomas (NHL). Binding to CD20 antigen is necessary for the antitumor effect of Rituxan®.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL whole blood or bone marrow collected in a sodium heparin (green-top) tube or EDTA (lavender-top) tube or ACD solution B (yellow-top) tube
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: Unacceptable
- Frozen: Unacceptable
Limitations
N/A
Other Acceptable Specimens
5 mL buffy coat or fresh (unfixed) tissue • CSF or tissue biopsy or fluid or pleural fluid
Unacceptable Specimens
Clotted or fixed sample
Order Code
RITUXN
EPIC (Premier) Code
LAB6159
Includes
N/A
CPT Code
- 86356
Billing Code
- 700000
CPT Statement
Methodology
Flow Cytometry (FC)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Daily; Report available: 2 - 3 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL whole blood or bone marrow collected in a sodium heparin (green-top) tube or EDTA (lavender-top) tube or ACD solution B (yellow-top) tube
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: Unacceptable
- Frozen: Unacceptable
Limitations
N/A
Other Acceptable Specimens
5 mL buffy coat or fresh (unfixed) tissue • CSF or tissue biopsy or fluid or pleural fluid
Unacceptable Specimens
Clotted or fixed sample
Result Information
Methodology
Flow Cytometry (FC)
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Daily; Report available: 2 - 3 days