PTH, Intact, Fine Needle Aspirate
Order Code:
PTHFNA
Test Summary
Surgical treatment of hyperparathyroidism relies on the ability to accurately identify parathyroid tissue. The use of fine-needle aspirate (FNA) with measurement of intact parathyroid hormone (PTH) levels in suspected parathyroid cysts or adenomas is used to identify parathyroid tissue and has been proven to be a useful surgical adjunct in the treatment of hyperparathyroidism.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL fine needle aspirate (FNA) collected in a sterile transport tube
Minimum Volume
0.8 mL
Instructions
A 25-gauge needle is inserted obliquely within the transducer plane of view and moved back and forth (passes) through the nodule to compensate for patient movement and needle deflection. There is no suction device; cells move into the needle via capillary action. After collection of the cytology samples, withdraw between 0.10 and 0.25 mL of saline up through each needle and empty this fluid back through the needle into a tube. This is the needle washing used for analysis. Repeat the passes and saline washings from the same biopsied site and empty contents into the same tube. The washes from all needles are pooled (final volume 1 mL). Inspect specimen for visible blood or tissue contamination. If bloody, centrifuge specimen and transfer supernatant to a new tube to send to the laboratory. The supernatant, not the cellular materials, is used for analysis. If the specimen is clear, centrifugation is not necessary.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 2 hours
- Refrigerated: 48 hours
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
Parathyroid-tissue washings • Non-lymph node washings • Non-nodal soft tissue washings or cervical node washings collected in a sterile transport tube
Unacceptable Specimens
Specimens in glass tubes • Any specimen type other than those listed in the Preferred or Other Acceptable section
Order Code
PTHFNA
EPIC (Premier) Code
LAB5981
Includes
N/A
CPT Code
- 83970
Billing Code
- 670445
CPT Statement
Methodology
Beckman Coulter Chemiluminescent
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
| Not suggestive of parathyroid tissue | <30 pg/mL |
| Compatible with parathyroid tissue | >100 pg/mL |
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Saturday; Report available: 3 - 5 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL fine needle aspirate (FNA) collected in a sterile transport tube
Minimum Volume
0.8 mL
Instructions
A 25-gauge needle is inserted obliquely within the transducer plane of view and moved back and forth (passes) through the nodule to compensate for patient movement and needle deflection. There is no suction device; cells move into the needle via capillary action. After collection of the cytology samples, withdraw between 0.10 and 0.25 mL of saline up through each needle and empty this fluid back through the needle into a tube. This is the needle washing used for analysis. Repeat the passes and saline washings from the same biopsied site and empty contents into the same tube. The washes from all needles are pooled (final volume 1 mL). Inspect specimen for visible blood or tissue contamination. If bloody, centrifuge specimen and transfer supernatant to a new tube to send to the laboratory. The supernatant, not the cellular materials, is used for analysis. If the specimen is clear, centrifugation is not necessary.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 2 hours
- Refrigerated: 48 hours
- Frozen: 28 days
Limitations
N/A
Other Acceptable Specimens
Parathyroid-tissue washings • Non-lymph node washings • Non-nodal soft tissue washings or cervical node washings collected in a sterile transport tube
Unacceptable Specimens
Specimens in glass tubes • Any specimen type other than those listed in the Preferred or Other Acceptable section
Result Information
Methodology
Beckman Coulter Chemiluminescent
Testing Laboratory
N/A
Reference Range
| Not suggestive of parathyroid tissue | <30 pg/mL |
| Compatible with parathyroid tissue | >100 pg/mL |
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday, Saturday; Report available: 3 - 5 days