Prothrombin Fragment 1.2
Test Summary
When prothrombin is converted to thrombin, the prothrombin fragment 1.2 is released from prothrombin. The test is useful to assess ongoing coagulation activation as may occur in thrombosis or DIC.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL frozen platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.5 mL
Instructions
Platelet-poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 4 hours
- Refrigerated: 4 hours
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received room temperature • Received refrigerated
Order Code
PTFRAG
EPIC (Premier) Code
LAB6386
Includes
N/A
CPT Code
- 83520
Billing Code
- 671029
CPT Statement
Methodology
Enzyme Immunoassay (EIA)
FDA Status
FDA Approved
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
| ADULT | 41-372 pmol/L |
Setup Schedule / Expected Turnaround Time
Wednesday; Report available: 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL frozen platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
Minimum Volume
0.5 mL
Instructions
Platelet-poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 4 hours
- Refrigerated: 4 hours
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Received room temperature • Received refrigerated
Result Information
Methodology
Enzyme Immunoassay (EIA)
Testing Laboratory
N/A
Reference Range
| ADULT | 41-372 pmol/L |
Setup Schedule / Expected Turnaround Time
Wednesday; Report available: 4 days