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Test Directory » Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G

Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G

Order Code: PAI1X

Test Summary

Plasma plasminogen activator inhibitor, PAI-1 is a major inhibitor of fibrinolysis. The 4G variant (AF386492.2:g.837del) in the PAI-1 (Serpine 1) gene promoter region is associated with an increase in the level of PAI-1 in plasma. Increased levels of PAI-1 in plasma may increase the risk for arterial and venous thrombosis, myocardial infarction, and progression of atherosclerosis and also recurrent spontaneous abortion.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

3 mL

Instructions

⁠⁠⁠⁠⁠⁠⁠Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship room temperature immediately. Do not freeze.

Forward tissue and extracted DNA specimens immediately to the Molecular Genetics Laboratory; do not hold.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 8 days
  • Refrigerated: 8 days
  • Frozen: Unacceptable

Limitations

N/A

Other Acceptable Specimens

Whole blood collected in: Sodium heparin (green-top) tube, ACD solution A or B (yellow-top) tube, or lithium heparin (green-top) tube

Unacceptable Specimens

N/A

Order Code

PAI1X

EPIC (Premier) Code

LAB3159

Includes

N/A

CPT Code

  • 81400

Billing Code

  • 670864

CPT Statement

CPT Statement

Methodology

Polymerase Chain Reaction and Detection

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Department

Reference Testing

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Wednesday, Saturday; Report available: 7 - 11 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

5 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

3 mL

Instructions

⁠⁠⁠⁠⁠⁠⁠Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship room temperature immediately. Do not freeze.

Forward tissue and extracted DNA specimens immediately to the Molecular Genetics Laboratory; do not hold.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 8 days
  • Refrigerated: 8 days
  • Frozen: Unacceptable

Limitations

N/A

Other Acceptable Specimens

Whole blood collected in: Sodium heparin (green-top) tube, ACD solution A or B (yellow-top) tube, or lithium heparin (green-top) tube

Unacceptable Specimens

N/A

Billing

CPT Code

  • 81400

Billing Code

  • 670864

CPT Statement

CPT Statement

Result Information

Methodology

Polymerase Chain Reaction and Detection

Testing Laboratory

N/A

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Wednesday, Saturday; Report available: 7 - 11 days