FISH, Myeloma, Chromosomes CEP 9, 11, 15
Test Summary
Plasma Cell Myeloma (PCM) is characterized by the proliferation of malignant monoclonal plasma cells in the bone marrow. Hyperdiploidy with gains of odd numbered chromosomes, including 9, 11, and 15, has been associated with a more favorable outcome in myeloma patients. This test replaces FISH, Multiple Myeloma (5, 9, 15), which is no longer available.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL bone marrow collected in a sodium heparin (green-top) tube
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Limitations
N/A
Other Acceptable Specimens
Sodium heparin (royal blue-top) tube • Sodium heparin lead-free (tan-top) tube
Unacceptable Specimens
N/A
Order Code
MYELCH
EPIC (Premier) Code
LAB5643
Includes
N/A
CPT Code
- 88271(x3)
- 88275
Billing Code
- 670950
- 670951
CPT Statement
Methodology
Fluorescence In Situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Daily; Report available: 7 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3 mL bone marrow collected in a sodium heparin (green-top) tube
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Limitations
N/A
Other Acceptable Specimens
Sodium heparin (royal blue-top) tube • Sodium heparin lead-free (tan-top) tube
Unacceptable Specimens
N/A
Result Information
Methodology
Fluorescence In Situ Hybridization (FISH)
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Daily; Report available: 7 days