Methylmalonic Acid, Urine with Creatinine
Test Summary
Methylmalonic Acid (MMA) is useful to diagnose and monitor Vitamin B12 (cobalamin) deficiency, and to diagnose and monitor patients with methylmalonic acidemia.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1.7 mL urine - no preservative in a sterile screw cap container
Minimum Volume
0.6 mL
Instructions
Do not use preservatives
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 4 days
- Refrigerated: 12 days
- Frozen -20°: 30 days
- Frozen -70°: 90 days
Limitations
N/A
Other Acceptable Specimens
In a sterile, screw-cap container (no preservative): 24-hour urine • Random clean-catch urine • Catheterized urine • First void clean-catch
Unacceptable Specimens
Received room temperature • Acidified urine
Order Code
MMAUR
EPIC (Premier) Code
LAB5391
Includes
N/A
CPT Code
- 82570
- 83921
Billing Code
- 670334
- 670333
CPT Statement
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
| Methylmalonic Acid, Urine | 0.3-2.2 mmol/mol creat |
Creatinine, Random Urine
| 0-6 Months | 0.18-2.48 mmol/L |
| 7-11 Months | 0.18-2.74 mmol/L |
| 1-2 Years | 0.18-9.72 mmol/L |
| 3-8 Years | 0.18-11.49 mmol/L |
| 9-12 Years | 0.18-14.14 mmol/L |
| >12 Years | 1.77-23.31 mmol/L |
Setup Schedule / Expected Turnaround Time
Evening 2 days a week.
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1.7 mL urine - no preservative in a sterile screw cap container
Minimum Volume
0.6 mL
Instructions
Do not use preservatives
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 4 days
- Refrigerated: 12 days
- Frozen -20°: 30 days
- Frozen -70°: 90 days
Limitations
N/A
Other Acceptable Specimens
In a sterile, screw-cap container (no preservative): 24-hour urine • Random clean-catch urine • Catheterized urine • First void clean-catch
Unacceptable Specimens
Received room temperature • Acidified urine
Result Information
Methodology
Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
| Methylmalonic Acid, Urine | 0.3-2.2 mmol/mol creat |
Creatinine, Random Urine
| 0-6 Months | 0.18-2.48 mmol/L |
| 7-11 Months | 0.18-2.74 mmol/L |
| 1-2 Years | 0.18-9.72 mmol/L |
| 3-8 Years | 0.18-11.49 mmol/L |
| 9-12 Years | 0.18-14.14 mmol/L |
| >12 Years | 1.77-23.31 mmol/L |
Setup Schedule / Expected Turnaround Time
Evening 2 days a week.