Liver Fibrosis, FibroTest-ActiTest Panel
Test Summary
FibroTest and ActiTest permit the non-invasive evaluation of Hepatitis C (or B) individuals for the presence of liver fibrosis and liver inflammation, respectively. The FibroTest and ActiTest scores are calculated based on patient age, gender and concentrations of serum of y-glutamyl transferase (GGT), total bilirubin (TB), a-2 macroglobulin, haptoglobin, apolipoprotein A1 and alanine aminotransferase (ActiTest). Fibrotest and ActiTest Scores, on a scale of 0.0 to 1.0, are assigned a Metavir scale indicating the level of fibrosis or inflammation present.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3.5 mL serum
Minimum Volume
2 mL
Instructions
Serum should be separated from the cells as soon as possible after visible clot formation (usually 15-30 minutes after collection). Avoid freezing and thawing.
Patient Preparation
Overnight fasting is preferred
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 72 hours
- Frozen -20° C: 5 days
- Frozen -70° C: 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic • Patients <2 years old • QNS for one or more analytes
Order Code
LVRFIB
EPIC (Premier) Code
LAB5702
Includes
Fibrosis Score, Fibrosis Stage, Fibrosis Interpretation
Necroinflammat Act Score, Necroinflammat Act Grade, Necroinflammat Interpretation
Alpha-2-Macroglobulin
Haptoglobin
Apolipoprotein A1
Total Bilirubin
GGT
ALT
Necroinflammat Act Score, Necroinflammat Act Grade, Necroinflammat Interpretation
Alpha-2-Macroglobulin
Haptoglobin
Apolipoprotein A1
Total Bilirubin
GGT
ALT
CPT Code
- 81596
Billing Code
- 700000
CPT Statement
Methodology
Nephelometry • Spectrophotometry (SP)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 2 - 5 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
3.5 mL serum
Minimum Volume
2 mL
Instructions
Serum should be separated from the cells as soon as possible after visible clot formation (usually 15-30 minutes after collection). Avoid freezing and thawing.
Patient Preparation
Overnight fasting is preferred
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 72 hours
- Frozen -20° C: 5 days
- Frozen -70° C: 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic • Patients <2 years old • QNS for one or more analytes
Result Information
Methodology
Nephelometry • Spectrophotometry (SP)
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 2 - 5 days