Hu Antibody Screen with Reflex to Titer and Western Blot
Test Summary
Paraneoplastic Syndrome involves non-metastatic systemic effects that accompany malignant disease. Antineuronal Nuclear Antibody (Anti-Hu) is found in 5-10% of patients with small cell carcinoma of the lung. Anti-Hu is associated with subacute syndrome of encephalomyeloradiculopathy, sensory neuropathy, and autoimmune neuropathy, predominantly affecting the gastrointestinal tract.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum
Minimum Volume
0.2 mL
Instructions
A fasting sample is required.
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 21 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Order Code
HUABRF
EPIC (Premier) Code
LAB3869
Includes
If Hu Antibody Screen, IFA is positive, then Hu Antibody, WB will be performed at an additional charge (CPT code(s): 84181).
If Hu Antibody, WB is positive, then Hu Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
If Hu Antibody, WB is positive, then Hu Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
CPT Code
- 86255
Billing Code
- 670071
CPT Statement
Methodology
Immunofluorescence Assay (IFA) • Western Blot (WB)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
| Hu Ab Screen, IFA | Negative |
| Hu Ab, WB | Negative |
| Hu Ab Titer | <1:40 |
Setup Schedule / Expected Turnaround Time
Monday, Wednesday, Friday; Report available: 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum
Minimum Volume
0.2 mL
Instructions
A fasting sample is required.
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 21 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Result Information
Methodology
Immunofluorescence Assay (IFA) • Western Blot (WB)
Testing Laboratory
N/A
Reference Range
| Hu Ab Screen, IFA | Negative |
| Hu Ab, WB | Negative |
| Hu Ab Titer | <1:40 |
Setup Schedule / Expected Turnaround Time
Monday, Wednesday, Friday; Report available: 4 days