HIV-1 Genotype (RTI, PI, Integrase Inhibitors)
Test Summary
Identify drug resistance mutations in HIV-1 patients failing antiretroviral regimens containing RT, PR or Integrase inhibitors.
Identify transmitted drug resistance mutations in the RT, PR or integrase genes in treatment-naive patients prior to initiation of antiretroviral therapy.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL plasma collected in an EDTA (lavender top) or PPT (white top) tube
Minimum Volume
1.2 mL
Instructions
Do not freeze whole blood or any samples stored in primary tube. Freshly drawn specimens (whole blood) may be stored at 2-25°C for up to 24 hours prior to centrifugation. Separate plasma from cells within 24 hours of collection by centrifugation. If shipping frozen, transfer plasma to a leak-proof transport tube, then freeze prior to shipment. Follow manufacturer's instructions for collection tube handling.
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 6 days
- Frozen: 42 days
Limitations
N/A
Other Acceptable Specimens
CSF collected in a sterile leak-proof container
Unacceptable Specimens
Plasma received frozen in the plasma preparation tube (PPT) • Serum • Whole blood greater than 24 hours old • Frozen whole blood
Order Code
HIVING
EPIC (Premier) Code
LAB6186
Includes
HIV-1 Integrase Genotype
HIV-1 Genotype
HIV-1 Genotype
CPT Code
- 87900
- 87901
- 87906
Billing Code
- 671013
- 670002
- 670001
CPT Statement
Methodology
Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) • Sequencing
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 4 - 9 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
4 mL plasma collected in an EDTA (lavender top) or PPT (white top) tube
Minimum Volume
1.2 mL
Instructions
Do not freeze whole blood or any samples stored in primary tube. Freshly drawn specimens (whole blood) may be stored at 2-25°C for up to 24 hours prior to centrifugation. Separate plasma from cells within 24 hours of collection by centrifugation. If shipping frozen, transfer plasma to a leak-proof transport tube, then freeze prior to shipment. Follow manufacturer's instructions for collection tube handling.
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 6 days
- Frozen: 42 days
Limitations
N/A
Other Acceptable Specimens
CSF collected in a sterile leak-proof container
Unacceptable Specimens
Plasma received frozen in the plasma preparation tube (PPT) • Serum • Whole blood greater than 24 hours old • Frozen whole blood
Result Information
Methodology
Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) • Sequencing
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 4 - 9 days