Hepatitis B Virus Drug Resistance, Genotype, and BCP/Precore Mutations
Order Code: HBVGEN
Test Summary
This test is used to:
1. Identify HBV genotype (A-H) for epidemiology or prognostic purposes.
2. Detect hepatitis B virus (HBV) mutations associated with resistance to antiviral agents.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL plasma collected in a PPT potassium EDTA (white-top) tube
Minimum Volume
0.3 mL
Instructions
Serum: Collect blood in sterile tubes with no anticoagulants; plastic serum separator tubes (SSTs) are recommended. Allow blood to clot at room temperature and separate serum from cells within 2 hours of collection. Transfer serum to sterile, plastic screw-capped, aliquot tubes and store refrigerated or frozen. Ship frozen.
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: 7 days
- Frozen: 30 days
Limitations
This test can only be performed reliably on specimens with a viral load of at least 600 IU/mL. For unknown viral loads order TC 16694.
Other Acceptable Specimens
Serum • Plasma collected in an EDTA (lavender-top) tube
Unacceptable Specimens
Unspun PPT tube
Order Code
HBVGEN
EPIC (Premier) Code
LAB3055
Includes
N/A
CPT Code
- 87912
Billing Code
- 671005
CPT Statement
Methodology
Polymerase Chain Reaction (PCR) • Sequencing
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday, Thurdays; Report available: 8 - 12 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL plasma collected in a PPT potassium EDTA (white-top) tube
Minimum Volume
0.3 mL
Instructions
Serum: Collect blood in sterile tubes with no anticoagulants; plastic serum separator tubes (SSTs) are recommended. Allow blood to clot at room temperature and separate serum from cells within 2 hours of collection. Transfer serum to sterile, plastic screw-capped, aliquot tubes and store refrigerated or frozen. Ship frozen.
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 72 hours
- Refrigerated: 7 days
- Frozen: 30 days
Limitations
This test can only be performed reliably on specimens with a viral load of at least 600 IU/mL. For unknown viral loads order TC 16694.
Other Acceptable Specimens
Serum • Plasma collected in an EDTA (lavender-top) tube
Unacceptable Specimens
Unspun PPT tube
Result Information
Methodology
Polymerase Chain Reaction (PCR) • Sequencing
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday, Thurdays; Report available: 8 - 12 days