First Trimester Screen, hCG
Order Code:
FTHCG
Test Summary
To screen for Down Syndrome and Trisomy 18 at 10.0-13.9 weeks gestation.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1.5 mL serum
Minimum Volume
0.8 mL
Instructions
Collect between 10.0 weeks to 13.9 (13 6/7) weeks. Perform between 10.0 to 13.9 (13 6/7) weeks gestational age. A special Maternal Serum Screen requisition designed to obtain patient data and the patient's informed consent must be used when ordering this test, because these results are influenced by certain patient characteristics. All data requested on the requisition form must be complete to permit accurate interpretation of results.
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 14 days
- Refrigerated: 14 days
- Frozen: 28 days
Limitations
First Trimester Screen results consistent with increased risk of trisomy should be confirmed with CVS or amniotic fluid specimen. Maternal serum screening yields a low percentage of false negatives. A wide range of other chromosomal abnormalities are not identified by maternal serum screening.
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis
Order Code
FTHCG
EPIC (Premier) Code
LAB5176
Includes
PAPP-A (Pregnancy-associated Plasma Protein-A), hCG, Maternal Risk calculation which includes NT (Nuchal Translucency)
CPT Code
- 84163
- 84702 OR 81508* *The 2017 AMA CPT codebook contains the component CPT codes and the new MAAA codeset. Please direct any questions regarding coding to the payor being billed.
Billing Code
- 670406
- 670407
- 670408
CPT Statement
Methodology
Calculation (CALC) • Chemiluminescence (CL) • Immunoassay (IA)
FDA Status
*PAPP-A Component only: This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
- MSS Down Syndrome Risk: <1:270
- MSS Trisomy 18 Risk: <1:100
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 4 - 6 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1.5 mL serum
Minimum Volume
0.8 mL
Instructions
Collect between 10.0 weeks to 13.9 (13 6/7) weeks. Perform between 10.0 to 13.9 (13 6/7) weeks gestational age. A special Maternal Serum Screen requisition designed to obtain patient data and the patient's informed consent must be used when ordering this test, because these results are influenced by certain patient characteristics. All data requested on the requisition form must be complete to permit accurate interpretation of results.
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 14 days
- Refrigerated: 14 days
- Frozen: 28 days
Limitations
First Trimester Screen results consistent with increased risk of trisomy should be confirmed with CVS or amniotic fluid specimen. Maternal serum screening yields a low percentage of false negatives. A wide range of other chromosomal abnormalities are not identified by maternal serum screening.
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis
Billing
CPT Code
- 84163
- 84702 OR 81508* *The 2017 AMA CPT codebook contains the component CPT codes and the new MAAA codeset. Please direct any questions regarding coding to the payor being billed.
Billing Code
- 670406
- 670407
- 670408
CPT Statement
Result Information
Methodology
Calculation (CALC) • Chemiluminescence (CL) • Immunoassay (IA)
Testing Laboratory
N/A
Reference Range
- MSS Down Syndrome Risk: <1:270
- MSS Trisomy 18 Risk: <1:100
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 4 - 6 days