Estradiol, Ultrasensitive, LC/MS
Test Summary
Diagnostic applications of estradiol assays include assessment of ovarian function in a wide variety of situations (menstrual disorders, precocious or delayed puberty, assisted reproduction protocols). For men, estradiol measurement may be useful in the evaluation of gynecomastia.
Aliases
- E2 IVF
- E2 Rapid
- E2
- Estrdiol
- Estradiol Level
- Estradiol Comment: Males only
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.2 mL
Instructions
Specify age and sex on test request form
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated
Specimen Stability
- Room Temperature = 24 hours
- Refrigerated = 7 days
- Frozen = 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tube • grossly icteric; lipemia
Order Code
ESTULT
EPIC (Premier) Code
LAB2108
Includes
N/A
CPT Code
- 82670
Billing Code
- 670284
CPT Statement
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
Adult Reference Ranges for Estradiol, Ultrasensitive
Pediatric Reference Ranges for Estradiol, Ultrasensitive
| Males | ≤29 pg/mL |
| Females | |
| Follicular Phase | 39-375 pg/mL |
| Luteal Phase | 48-440 pg/mL |
| Postmenopausal Phase | ≤10 pg/mL |
Pediatric Reference Ranges for Estradiol, Ultrasensitive
| Age | Males (pg/mL) | Females (pg/mL) |
| Pre-pubertal | ||
| <1 year | Not Established | Not Established |
| 1-9 years | ≤4 | ≤16 |
| 10-11 years | ≤12 | ≤65 |
| 12-14 years | ≤24 | ≤142 |
| 15-17 years | ≤31 | ≤283 |
Setup Schedule / Expected Turnaround Time
Sunday - Friday evenings; Report available: 3 - 6 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.2 mL
Instructions
Specify age and sex on test request form
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated
Specimen Stability
- Room Temperature = 24 hours
- Refrigerated = 7 days
- Frozen = 28 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tube • grossly icteric; lipemia
Result Information
Methodology
Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
Adult Reference Ranges for Estradiol, Ultrasensitive
Pediatric Reference Ranges for Estradiol, Ultrasensitive
| Males | ≤29 pg/mL |
| Females | |
| Follicular Phase | 39-375 pg/mL |
| Luteal Phase | 48-440 pg/mL |
| Postmenopausal Phase | ≤10 pg/mL |
Pediatric Reference Ranges for Estradiol, Ultrasensitive
| Age | Males (pg/mL) | Females (pg/mL) |
| Pre-pubertal | ||
| <1 year | Not Established | Not Established |
| 1-9 years | ≤4 | ≤16 |
| 10-11 years | ≤12 | ≤65 |
| 12-14 years | ≤24 | ≤142 |
| 15-17 years | ≤31 | ≤283 |
Setup Schedule / Expected Turnaround Time
Sunday - Friday evenings; Report available: 3 - 6 days