Estrone
Test Summary
Estrone is primarily derived from metabolism of androstenedione in peripheral tissues, especially adipose tissues. Individuals with obesity have increased conversion of androstenedione to Estrone leading to higher concentrations. In addition, an increase in the ratio of Estrone to Estradiol may be useful in assessing menopause in women.
Aliases
- E1
- E1 Estrone
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.25 mL
Instructions
Specify age and sex on test requisition
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hrs
- Refrigerated: 30 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tube (SST) • Gross hemolysis
Order Code
ESTRON
EPIC (Premier) Code
LAB560
Includes
N/A
CPT Code
- 82679
Billing Code
- 670282
CPT Statement
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
| Adult | |
| Male | ≤68 pg/mL |
| Female | |
| Follicular Phase | 10-138 pg/mL |
| Luteal Phase | 16-173 pg/mL |
| Postmenopausal Phase | ≤65 pg/mL |
Pediatric
| Age | Male (pg/mL) | Female (pg/mL) |
| Pre-pubertal (1-9 years) | <10 | ≤34 |
| 10-11 years | ≤12 | ≤72 |
| 12-14 years | ≤28 | ≤75 |
| 15-17 years | ≤64 | ≤188 |
Setup Schedule / Expected Turnaround Time
Daily; Report available: 2 - 5 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.25 mL
Instructions
Specify age and sex on test requisition
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hrs
- Refrigerated: 30 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Serum separator tube (SST) • Gross hemolysis
Result Information
Methodology
Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
| Adult | |
| Male | ≤68 pg/mL |
| Female | |
| Follicular Phase | 10-138 pg/mL |
| Luteal Phase | 16-173 pg/mL |
| Postmenopausal Phase | ≤65 pg/mL |
Pediatric
| Age | Male (pg/mL) | Female (pg/mL) |
| Pre-pubertal (1-9 years) | <10 | ≤34 |
| 10-11 years | ≤12 | ≤72 |
| 12-14 years | ≤28 | ≤75 |
| 15-17 years | ≤64 | ≤188 |
Setup Schedule / Expected Turnaround Time
Daily; Report available: 2 - 5 days