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Test Directory

Estriol, Serum

Test Summary

The placenta converts DHEA-S, produced by the fetal adrenals, to Estriol and other estrogens. Estriol is useful in assessing the fetal adrenals and placenta during pregnancy. More commonly, Estriol is one of the maternal serum biochemical markers used to screen for common chromosomal trisomies, especially Down syndrome.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

0.5 mL serum collected in a red-top tube (no-gel)

Minimum Volume

0.3 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 5 days
  • Refrigerated: 7 days
  • Frozen: 28 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Serum separator tube (SST®)

Order Code

ESTRL

EPIC (Premier) Code

LAB173

Includes

N/A

CPT Code

  • 82677

Billing Code

  • 670281

CPT Statement

Methodology

Chromatography/Mass Spectrometry

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Department

Reference Testing

Reference Range

Adult Males≤0.18 ng/mL
Adult Females (non-pregnant)≤0.21 ng/mL
   
Pregnancy
  First Trimester≤2.50 ng/mL
  Second Trimester≤9.60 ng/mL
  Third Trimester≤14.60 ng/mL

Setup Schedule / Expected Turnaround Time

Sunday - Friday; Report available: 3 - 5 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

0.5 mL serum collected in a red-top tube (no-gel)

Minimum Volume

0.3 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 5 days
  • Refrigerated: 7 days
  • Frozen: 28 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Serum separator tube (SST®)

Billing

CPT Code

  • 82677

Billing Code

  • 670281

CPT Statement

Result Information

Methodology

Chromatography/Mass Spectrometry

Testing Laboratory

N/A

Reference Range

Adult Males≤0.18 ng/mL
Adult Females (non-pregnant)≤0.21 ng/mL
   
Pregnancy
  First Trimester≤2.50 ng/mL
  Second Trimester≤9.60 ng/mL
  Third Trimester≤14.60 ng/mL

Setup Schedule / Expected Turnaround Time

Sunday - Friday; Report available: 3 - 5 days