Dengue Fever Antibody (IgG)
Test Summary
Dengue and dengue hemorrhagic fever result from infection by any of four serotypes of dengue viruses. Transmission occurs through the bite of infected Aedes mosquitos. In most patients, Dengue Virus antibodies are detectable after the sixth day following the onset of symptoms. Strong cross-reactivity is seen with other group B arboviruses (flavivirus), including St. Louis encephalitis, Japanese B encephalitis, Rio Bravo, Powassan, and Yellow Fever viruses.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.5 mL serum
Minimum Volume
0.1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis • Icteric • Lipemia
Order Code
DENGFG
EPIC (Premier) Code
LAB5833
Includes
N/A
CPT Code
- 86790
Billing Code
- 670900
CPT Statement
Methodology
Immunoassay (IA)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
<0.80
Interpretive Criteria
This assay detects IgG antibodies against all four Dengue virus types, and the antibody response to Dengue fever is not type specific.
The presence of IgG in the absence of IgM may Indicate either recent or past infection. Before day 6 of symptoms, both IgM and IgG may be negative, and alternate testing (Dengue NS-1 Antigen or Dengue PCR) is recommended. Cross-reactivity with other flaviviruses is known to occur; the extent and degree of serologic cross-reactivity varies.
Interpretive Criteria
| <0.80 | Negative |
| 0.80-1.09 | Equivocal |
| ≥1.10 | Positive |
The presence of IgG in the absence of IgM may Indicate either recent or past infection. Before day 6 of symptoms, both IgM and IgG may be negative, and alternate testing (Dengue NS-1 Antigen or Dengue PCR) is recommended. Cross-reactivity with other flaviviruses is known to occur; the extent and degree of serologic cross-reactivity varies.
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday morning; Report available: 2 - 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
0.5 mL serum
Minimum Volume
0.1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis • Icteric • Lipemia
Result Information
Methodology
Immunoassay (IA)
Testing Laboratory
N/A
Reference Range
<0.80
Interpretive Criteria
This assay detects IgG antibodies against all four Dengue virus types, and the antibody response to Dengue fever is not type specific.
The presence of IgG in the absence of IgM may Indicate either recent or past infection. Before day 6 of symptoms, both IgM and IgG may be negative, and alternate testing (Dengue NS-1 Antigen or Dengue PCR) is recommended. Cross-reactivity with other flaviviruses is known to occur; the extent and degree of serologic cross-reactivity varies.
Interpretive Criteria
| <0.80 | Negative |
| 0.80-1.09 | Equivocal |
| ≥1.10 | Positive |
The presence of IgG in the absence of IgM may Indicate either recent or past infection. Before day 6 of symptoms, both IgM and IgG may be negative, and alternate testing (Dengue NS-1 Antigen or Dengue PCR) is recommended. Cross-reactivity with other flaviviruses is known to occur; the extent and degree of serologic cross-reactivity varies.
Setup Schedule / Expected Turnaround Time
Tuesday - Saturday morning; Report available: 2 - 4 days