Cysticercus Antibody (IgG), Western Blot, Serum
Test Summary
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia Solium, the agent causing Cysticercosis. Detection of antibodies to any 6 specific T.solium glycoprotein bands of molecular weight 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reac- tivity to the 50 and 42-39 glycoprotein bands may reflect cross-reactive antibodies induced by Echinococcus.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic • Grossly icteric
Order Code
CYSTAB
EPIC (Premier) Code
LAB3779
Includes
N/A
CPT Code
- 86682
Billing Code
- 670243
CPT Statement
Methodology
Western Blot (WB)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
Negative
Interpretive Criteria
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia solium, the agent causing cysticercosis. Detection of antibodies to any of 6 specific T. solium glycoprotein bands of molecular weights 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reactivity to the 50 and 42-39 glycoprotein bands may reflect cross-reactive antibodies induced by echinococcosis.
A negative test result does not exclude the diagnosis of neurocysticercosis, particularly if only a single brain lesion is present. The sensitivity increases from 50% or less for a solitary brain cyst to greater than 90% if 3 or more cysts are present.
Interpretive Criteria
| Negative | None of 6 specific bands detected |
| Positive | One or more of 6 specific bands detected |
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia solium, the agent causing cysticercosis. Detection of antibodies to any of 6 specific T. solium glycoprotein bands of molecular weights 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reactivity to the 50 and 42-39 glycoprotein bands may reflect cross-reactive antibodies induced by echinococcosis.
A negative test result does not exclude the diagnosis of neurocysticercosis, particularly if only a single brain lesion is present. The sensitivity increases from 50% or less for a solitary brain cyst to greater than 90% if 3 or more cysts are present.
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday; Report available: 2 - 5 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
N/A
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Gross hemolysis • Grossly lipemic • Grossly icteric
Result Information
Methodology
Western Blot (WB)
Testing Laboratory
N/A
Reference Range
Negative
Interpretive Criteria
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia solium, the agent causing cysticercosis. Detection of antibodies to any of 6 specific T. solium glycoprotein bands of molecular weights 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reactivity to the 50 and 42-39 glycoprotein bands may reflect cross-reactive antibodies induced by echinococcosis.
A negative test result does not exclude the diagnosis of neurocysticercosis, particularly if only a single brain lesion is present. The sensitivity increases from 50% or less for a solitary brain cyst to greater than 90% if 3 or more cysts are present.
Interpretive Criteria
| Negative | None of 6 specific bands detected |
| Positive | One or more of 6 specific bands detected |
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia solium, the agent causing cysticercosis. Detection of antibodies to any of 6 specific T. solium glycoprotein bands of molecular weights 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reactivity to the 50 and 42-39 glycoprotein bands may reflect cross-reactive antibodies induced by echinococcosis.
A negative test result does not exclude the diagnosis of neurocysticercosis, particularly if only a single brain lesion is present. The sensitivity increases from 50% or less for a solitary brain cyst to greater than 90% if 3 or more cysts are present.
Setup Schedule / Expected Turnaround Time
Tuesday, Thursday; Report available: 2 - 5 days