Chymotrypsin, Stool
Test Summary
The diagnosis of chronic pancreatitis depends upon the demonstration of functional impairment of the pancreas. Impairment is determined by several means, two of which are:
1. Direct measurement of exocrine secretion into the duodenum after stimulation by a standard meal or after stimulation by intravenous secretin/pancreozymin.
2. The direct measurement of the activities of certain enzymes in feces. Chymotrypsin activity in stool, for example, has been shown to be lower than normal in patients with pancreatic exocrine insufficiency.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 gram random stool collected in a sterile, leak-proof container
Minimum Volume
0.5 g
Instructions
N/A
Patient Preparation
Patients receiving pancreatic enzymes should discontinue taking the enzymes at least 5 days before the collection of the stool sample
Storage
Sterile Container, leak-proof
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Order Code
CHYMOT
EPIC (Premier) Code
LAB3139
Includes
N/A
CPT Code
- 84311
Billing Code
- 670199
CPT Statement
Methodology
Enzymatic/Spectrophotometric
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
2.3-51.4 U/g
Setup Schedule / Expected Turnaround Time
Wednesday morning; Report available: 3 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 gram random stool collected in a sterile, leak-proof container
Minimum Volume
0.5 g
Instructions
N/A
Patient Preparation
Patients receiving pancreatic enzymes should discontinue taking the enzymes at least 5 days before the collection of the stool sample
Storage
Sterile Container, leak-proof
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 14 days
- Frozen: 30 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Result Information
Methodology
Enzymatic/Spectrophotometric
Testing Laboratory
N/A
Reference Range
2.3-51.4 U/g
Setup Schedule / Expected Turnaround Time
Wednesday morning; Report available: 3 days