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Chromosome Analysis, Hematologic Malignancy

Test Summary

Cytogenetics of hematologic disorders attempts to define and interpret chromosomal aberrations that occur in neoplastic cells associated with leukemia, lymphoma and other hematologic malignancies. Chromosome abnormalities in cancer cells of patients with malignant hematologic disorders including acute and chronic myeloid and lymphoid leukemias, myelodysplastic and myeloproliferative disorders, lymphomas and unexplained anemias may correlate with the diagnosis, prognosis, treatment and etiology of disease.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

3 mL bone marrow or 10 mL whole blood collected in a sodium heparin (green-top) tube

Minimum Volume

1 mL

Instructions

Bone marrow 3 mL or whole blood 10 mL, must contain 10% less mature myelocytes, pros or blasts. (green Vacutainer® only).
Infants 2-3 mL (in pediatric 3 mL Vacutainer®), must contain 10% myelocytes, pros or blasts. Ship at room temperature.
Bone marrow transport medium is available upon request.

Note: See the "Cytogenetics" section of the specimen collection guide for additional information. Other Vacutainer® tubes containing sodium heparin are acceptable.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.

Limitations

N/A

Other Acceptable Specimens

Sodium heparin (royal blue-top) tube • Sodium heparin lead-free (tan-top) tube

Unacceptable Specimens

Received frozen

Order Code

CHROM

EPIC (Premier) Code

LAB3180

Includes

N/A

CPT Code

  • 88237
  • 88264

Billing Code

  • 671051
  • 671052

CPT Statement

Methodology

Culture • Karyotype • Microscopy

FDA Status

FDA Approved

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Department

Reference Testing

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Mornings; 7 days a week. Report available 8 - 9 days.

Specimen Collection

Special Instructions

N/A

Preferred Specimen

3 mL bone marrow or 10 mL whole blood collected in a sodium heparin (green-top) tube

Minimum Volume

1 mL

Instructions

Bone marrow 3 mL or whole blood 10 mL, must contain 10% less mature myelocytes, pros or blasts. (green Vacutainer® only).
Infants 2-3 mL (in pediatric 3 mL Vacutainer®), must contain 10% myelocytes, pros or blasts. Ship at room temperature.
Bone marrow transport medium is available upon request.

Note: See the "Cytogenetics" section of the specimen collection guide for additional information. Other Vacutainer® tubes containing sodium heparin are acceptable.

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

  • Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.

Limitations

N/A

Other Acceptable Specimens

Sodium heparin (royal blue-top) tube • Sodium heparin lead-free (tan-top) tube

Unacceptable Specimens

Received frozen

Billing

CPT Code

  • 88237
  • 88264

Billing Code

  • 671051
  • 671052

CPT Statement

Result Information

Methodology

Culture • Karyotype • Microscopy

Testing Laboratory

N/A

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Mornings; 7 days a week. Report available 8 - 9 days.