Chromosome Analysis, Chorionic Villus Sample
Order Code:
CHRMCV
Test Summary
This test will detect chromosome abnormalities of the fetus including numerical, structural, and mosaic abnormalities. Chromosome analysis will also reveal fetal gender and sex chromosome abnormalities. Indications for prenatal chromosome analysis may include advanced maternal age, abnormal fetal ultrasound, abnormal maternal serum screen, abnormal cell-free DNA results, history of a previous child with a chromosome abnormality, or a parent who carries a balanced chromosomal rearrangement or has another chromosome abnormality.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
40 mg chorionic villi in Hanks', Ringer's solution or culture medium with antibiotics
Minimum Volume
20 mg
Instructions
Ship in sterile container in Hanks', Ringer's solution or culture medium with antibiotics. CVS media available upon request. Ship at room temperature.
Please contact the laboratory Genetic Counselor at 1-866-GENEINFO (1-866-436-3463) with any questions.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Please contact the laboratory Genetic Counselor at 1-866-GENEINFO (1-866-436-3463) with any questions.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: Preferred
- Refrigerated: Acceptable
- Frozen: Unacceptable
Limitations
Chromosome aberrations observed in the CVS specimen but not in the fetus (confined placental mosaicism) occurs in approximately 1% of cases.
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Order Code
CHRMCV
EPIC (Premier) Code
LAB495
Includes
N/A
CPT Code
- 88235
- 88267
- 88280
Billing Code
- 670916
- 670917
- 670918
CPT Statement
Methodology
Culture • Microscopy • Karyotype
FDA Status
FDA Approved
Physician Attestation of Informed Consent
This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, DE, FL, GA, IA, MA, MN, NV, NJ, NY, OR, SD or VT or test is performed in MA.
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
Interpretive report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 8 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
40 mg chorionic villi in Hanks', Ringer's solution or culture medium with antibiotics
Minimum Volume
20 mg
Instructions
Ship in sterile container in Hanks', Ringer's solution or culture medium with antibiotics. CVS media available upon request. Ship at room temperature.
Please contact the laboratory Genetic Counselor at 1-866-GENEINFO (1-866-436-3463) with any questions.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Please contact the laboratory Genetic Counselor at 1-866-GENEINFO (1-866-436-3463) with any questions.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: Preferred
- Refrigerated: Acceptable
- Frozen: Unacceptable
Limitations
Chromosome aberrations observed in the CVS specimen but not in the fetus (confined placental mosaicism) occurs in approximately 1% of cases.
Other Acceptable Specimens
N/A
Unacceptable Specimens
N/A
Result Information
Methodology
Culture • Microscopy • Karyotype
Testing Laboratory
N/A
Reference Range
Interpretive report
Setup Schedule / Expected Turnaround Time
Monday - Saturday; Report available: 8 days