C4d Fragment, EIA
Order Code:
C4DF
Test Summary
Clinical use is to exclude known rheumatoid arthritis, systemic lupus erythematosus, and chronic urticaria with hypocomplementemia. C4d is a stable activation product of C4 cleavage, and is useful to determine classical pathway complement activation.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL frozen plasma collected in an EDTA (lavender-top) tube
Minimum Volume
0.2 mL
Instructions
Barrier tubes (serum separator tubes or plasma separator tubes) are preferred. If non-barrier tubes are utilized, the serum/plasma must be removed immediately after centrifuging and placed in a screw-cap transfer tube. Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered. Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 4 hours
- Frozen: 14 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis • Serum • Gel barrier interferes with assay methodology
Order Code
C4DF
EPIC (Premier) Code
LAB3547
Includes
N/A
CPT Code
- 83520
Billing Code
- 670988
CPT Statement
Methodology
Enzyme Immunoassay (EIA)
FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
0.9-8.0 mcg/mL
Setup Schedule / Expected Turnaround Time
Tuesday night; Report available: 4 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1 mL frozen plasma collected in an EDTA (lavender-top) tube
Minimum Volume
0.2 mL
Instructions
Barrier tubes (serum separator tubes or plasma separator tubes) are preferred. If non-barrier tubes are utilized, the serum/plasma must be removed immediately after centrifuging and placed in a screw-cap transfer tube. Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered. Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
- Refrigerated: 4 hours
- Frozen: 14 days
Limitations
N/A
Other Acceptable Specimens
N/A
Unacceptable Specimens
Hemolysis • Serum • Gel barrier interferes with assay methodology
Result Information
Methodology
Enzyme Immunoassay (EIA)
Testing Laboratory
N/A
Reference Range
0.9-8.0 mcg/mL
Setup Schedule / Expected Turnaround Time
Tuesday night; Report available: 4 days