Beta-Globin Complete
Test Summary
1) To identify disease-causing mutations in individuals affected with beta-thalassemia.
2) To identify carriers in high-risk ethnic group or people with positive family history.
3) Prenatal diagnosis of beta-thalassemia.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL whole blood collected in a EDTA (lavender-top) tube, or ACD solution A or B (yellow-top) tube
Minimum Volume
3 mL
Instructions
Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship ambient immediately. Glass tubes should not be shipped frozen.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 30 days
- Refrigerated: 30 days
- Frozen: 30 days
Limitations
If these mutations are not found by the testing procedure, it does not mean that the risk of carrying or developing beta thalassemia is not present. It simply means that these specific mutations have not seen found with this assay, although other mutations may be present.
Other Acceptable Specimens
Whole blood collected in: sodium heparin (green-top) tube
Unacceptable Specimens
N/A
Order Code
BGLOBC
EPIC (Premier) Code
LAB5980
Includes
N/A
CPT Code
- 81364 for New York State patient testing
- use Test Code 14979 Beta-Globin Complete (NY)
Billing Code
- 670585
CPT Statement
Methodology
DNA Sequencing • Polymerase Chain Reaction (PCR)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, DE, FL, GA, IA, MA, MN, NV, NJ, NY, OR, SD or VT or test is performed in MA.
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday, Thursday; Report available: 15 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL whole blood collected in a EDTA (lavender-top) tube, or ACD solution A or B (yellow-top) tube
Minimum Volume
3 mL
Instructions
Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship ambient immediately. Glass tubes should not be shipped frozen.
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 30 days
- Refrigerated: 30 days
- Frozen: 30 days
Limitations
If these mutations are not found by the testing procedure, it does not mean that the risk of carrying or developing beta thalassemia is not present. It simply means that these specific mutations have not seen found with this assay, although other mutations may be present.
Other Acceptable Specimens
Whole blood collected in: sodium heparin (green-top) tube
Unacceptable Specimens
N/A
Billing
CPT Code
- 81364 for New York State patient testing
- use Test Code 14979 Beta-Globin Complete (NY)
Billing Code
- 670585
CPT Statement
Result Information
Methodology
DNA Sequencing • Polymerase Chain Reaction (PCR)
Testing Laboratory
N/A
Reference Range
See Laboratory Report
Setup Schedule / Expected Turnaround Time
Monday, Thursday; Report available: 15 days