Mantle Cell Lymphoma, bcl-1/JH, t(11;14), Cell-Based
Test Summary
Bcl-1/JH t(11;14) is highly specific for mantle cell lymphoma (MCL). The t(11;14) can be found in approximately 70% to 95% cases of MCL. Half of these translocations fall within the BCL-1 major translocation cluster (MTC). The t(11;14) Real-Time PCR assay can be used to monitor minimal residual disease in NHL. Ideally, recent patient samples should be tested side by side with the previous sample to better illustrate the quantitative changes.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL bone marrow or whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Bone marrow and whole blood:
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: Unacceptable
- Tissue block:
- Room temperature: Indefinitely
- Refrigerated: Unacceptable
- Fro
Limitations
N/A
Other Acceptable Specimens
Formalin-fixed, paraffin-embedded tissue block
Unacceptable Specimens
N/A
Order Code
BCL1JH
EPIC (Premier) Code
LAB3205
Includes
N/A
CPT Code
- 81168 -
Billing Code
- 670860
CPT Statement
Methodology
Real-Time Polymerase Chain Reaction (RT-PCR)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Department
Reference Testing
Reference Range
0/Negative
Setup Schedule / Expected Turnaround Time
Tuesday, Saturday; Report available: 3 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
5 mL bone marrow or whole blood collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Room temperature
Specimen Stability
- Bone marrow and whole blood:
- Room temperature: 7 days
- Refrigerated: 14 days
- Frozen: Unacceptable
- Tissue block:
- Room temperature: Indefinitely
- Refrigerated: Unacceptable
- Fro
Limitations
N/A
Other Acceptable Specimens
Formalin-fixed, paraffin-embedded tissue block
Unacceptable Specimens
N/A
Result Information
Methodology
Real-Time Polymerase Chain Reaction (RT-PCR)
Testing Laboratory
N/A
Reference Range
0/Negative
Setup Schedule / Expected Turnaround Time
Tuesday, Saturday; Report available: 3 days