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Test Directory

Test Directory Aquaporin-4 Antibody (IgG), CBA

Aquaporin-4 Antibody (IgG), CBA

Test Summary

Antibody to Aquaporin 4 causes neuromyelitis optica (NMO), a demyelinating disease of the central nervous system often confused diagnostically with multiple sclerosis (MS) and/or transverse myelitis. NMO causes optic neuritis and transverse myelitis. Early discrimination between MS and NMO is important, as optimum treatment for both diseases may differ considerably.

Aliases

Specimen Collection

Special Instructions

N/A

Preferred Specimen

0.5 mL serum collected in a red-top tube (no gel)

Minimum Volume

0.3 mL

Instructions

N/A

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 21 days

Limitations

N/A

Other Acceptable Specimens

0.5 mL CSF submitted in a sterile vial

Unacceptable Specimens

Serum separator tube (SST®)

Order Code

AQP4AB

EPIC (Premier) Code

LAB5823

Includes

N/A

CPT Code

86052

Billing Code

700000

CPT Statement

Methodology

Cell Binding Assay-Immunofluorescence Assay

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Reference Range

Negative

Setup Schedule / Expected Turnaround Time

Wednesday, Friday; Report available: 8 days