Schedule an Appointment Pay Bill View My Results

Test Directory

Test Directory FISH, AML, CBFB/MYH11, Inversion 16

FISH, AML, CBFB/MYH11, Inversion 16

Test Summary

This test is performed to detect the CBFB rearrangements such as inversion (16) and translocation t(16;16), by FISH (fluorescence in situ hybridization). This assay is useful for diagnosis of acute myeloid leukemia (AML) with inv(16) or t(16;16); CBFB-MYH11.

Aliases

Specimen Collection

Special Instructions

N/A

Preferred Specimen

5 mL whole blood or 3 mL bone marrow collected in a sodium heparin (green-top) tube

Minimum Volume

1 mL

Instructions

Bone marrow 1-3 mL, or whole blood 3-5 mL, sodium heparin only

Patient Preparation

N/A

Storage

N/A

Transport Temperature

Room temperature

Specimen Stability

Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not Reject.

Limitations

N/A

Other Acceptable Specimens

Sodium heparin (royal blue-top) tube • Sodium heparin lead-free (tan-top) tube

Unacceptable Specimens

N/A

Order Code

AMLINV

EPIC (Premier) Code

LAB3063

Includes

N/A

CPT Code

88271 (x2)
88275

Billing Code

670942
670943

CPT Statement

Methodology

Fluorescence In Situ Hybridization (FISH)

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Department

Reference Testing

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Mornings; 7 days a week. Report available: 5 - 7 days.