Aldosterone, 24-Hour Urine with Creatinine
Test Summary
Aldosterone is a hormone produced by the adrenal glands. Patients with primary hyperaldosteronism exhibit hypokalemia, hypertension, and low direct renin concentrations.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1.5 mL 24-hour urine collected in a 24-hour urine container
Minimum Volume
0.8 mL
Instructions
Record 24-hour urine volume on test requisition and urine vial. Refrigerate during and after collection.
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 28 days
- Frozen: 21 days
Limitations
N/A
Other Acceptable Specimens
Random urine collected in a no preservative container (reference ranges do not apply to random urine samples) • 24-hour urine collected in a 24-hour urine container with 10 g Boric acid
Unacceptable Specimens
Urine collected with HCl
Order Code
ALDOSU
EPIC (Premier) Code
LAB020
Includes
Creatinine
CPT code 81050 may be added at an additional charge for volume measurement
CPT code 81050 may be added at an additional charge for volume measurement
CPT Code
- 82088
- 82570
Billing Code
- 671330
- 670533
CPT Statement
Methodology
Hydrolysis • Extraction • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Reference Range
Aldosterone, 24-Hour Urine
Random Sodium Diet
Oral sodium loading test (high salt diet for 3 days): 12 mcg/24 hrs or less*
*Funder JW, Carey RM, Mantero F, et al. The Management of Primary
Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016; 101:1889-1916
Creatinine, 24-Hour Urine
Random Sodium Diet
| Age | mcg/24 hours |
| 2-7 years | 5.7 or less |
| 8-11 years | 10.2 or less |
| 12-16 years | 15.6 or less |
| Adults | 2.3-21.0 |
*Funder JW, Carey RM, Mantero F, et al. The Management of Primary
Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016; 101:1889-1916
Creatinine, 24-Hour Urine
| <3 Years | Not established |
| 3-8 Years | 0.10-0.80 g/24 h |
| 9-12 Years | 0.20-1.40 g/24 h |
| 13-17 Years | 0.40-1.90 g/24 h |
| >17 Years | 0.50-2.15 g/24 h |
Setup Schedule / Expected Turnaround Time
Sunday, Tuesday; Report available: 4 - 10 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
1.5 mL 24-hour urine collected in a 24-hour urine container
Minimum Volume
0.8 mL
Instructions
Record 24-hour urine volume on test requisition and urine vial. Refrigerate during and after collection.
Patient Preparation
N/A
Storage
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 28 days
- Frozen: 21 days
Limitations
N/A
Other Acceptable Specimens
Random urine collected in a no preservative container (reference ranges do not apply to random urine samples) • 24-hour urine collected in a 24-hour urine container with 10 g Boric acid
Unacceptable Specimens
Urine collected with HCl
Result Information
Methodology
Hydrolysis • Extraction • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Testing Laboratory
N/A
Reference Range
Aldosterone, 24-Hour Urine
Random Sodium Diet
Oral sodium loading test (high salt diet for 3 days): 12 mcg/24 hrs or less*
*Funder JW, Carey RM, Mantero F, et al. The Management of Primary
Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016; 101:1889-1916
Creatinine, 24-Hour Urine
Random Sodium Diet
| Age | mcg/24 hours |
| 2-7 years | 5.7 or less |
| 8-11 years | 10.2 or less |
| 12-16 years | 15.6 or less |
| Adults | 2.3-21.0 |
*Funder JW, Carey RM, Mantero F, et al. The Management of Primary
Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2016; 101:1889-1916
Creatinine, 24-Hour Urine
| <3 Years | Not established |
| 3-8 Years | 0.10-0.80 g/24 h |
| 9-12 Years | 0.20-1.40 g/24 h |
| 13-17 Years | 0.40-1.90 g/24 h |
| >17 Years | 0.50-2.15 g/24 h |
Setup Schedule / Expected Turnaround Time
Sunday, Tuesday; Report available: 4 - 10 days