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Advanced Lipid Panel, Cardio IQ®

Test Summary

The advanced lipid profile provides a more comprehensive assessment of dyslipidemia and cardiovascular risk than standard lipid panel measurements.

Aliases

  • N/A

Specimen Collection

Special Instructions

N/A

Preferred Specimen

3 mL serum AND 1 mL serum

Minimum Volume

1.75 mL AND 0.25 mL

Instructions

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for... Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Patient Preparation

If a Cholesterol measurement is to be performed along with Triglycerides, but not part of a Lipid Panel, then the patient should be fasting 9-12 hours prior to collection. If the Cholesterol is ordered as part of a Lipid Panel, then a fasting sample is not required.

Storage

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 24 hours
  • Refrigerated: 7 days
  • Frozen: 28 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly lipemic • Moderate to grossly icteric

Order Code

ADVLIP

EPIC (Premier) Code

LAB5587

Includes

Cardio IQ® Cholesterol, Total
Cardio IQ® HDL Cholesterol
Cardio IQ® Triglycerides
Cardio IQ® Non-HDL and Calculated Components
Cardio IQ® Lipoprotein Fractionation, Ion Mobility
Cardio IQ® Apolipoprotein B
Cardio IQ® Lipoprotein (a)

If Triglyceride is >400 mg/dL, then Cardio IQ® Direct LDL will be performed at an additional charge (CPT code(s): 83721).

CPT Code

  • 80061
  • 83704
  • 82172
  • 83695

Billing Code

  • 670807
  • 670815
  • 670816
  • 870817

CPT Statement

Methodology

Enzymatic • Spectrophotometric • Ion Mobility • Fixed Rate Nephelometry • Immunoturbidometric • Immunoassay (IA)

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Monday - Friday; Report available: 4 - 7 days

Specimen Collection

Special Instructions

N/A

Preferred Specimen

3 mL serum AND 1 mL serum

Minimum Volume

1.75 mL AND 0.25 mL

Instructions

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for... Cholesterol, Uric Acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Patient Preparation

If a Cholesterol measurement is to be performed along with Triglycerides, but not part of a Lipid Panel, then the patient should be fasting 9-12 hours prior to collection. If the Cholesterol is ordered as part of a Lipid Panel, then a fasting sample is not required.

Storage

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 24 hours
  • Refrigerated: 7 days
  • Frozen: 28 days

Limitations

N/A

Other Acceptable Specimens

N/A

Unacceptable Specimens

Gross hemolysis • Grossly lipemic • Moderate to grossly icteric

Billing

CPT Code

  • 80061
  • 83704
  • 82172
  • 83695

Billing Code

  • 670807
  • 670815
  • 670816
  • 870817

CPT Statement

Result Information

Methodology

Enzymatic • Spectrophotometric • Ion Mobility • Fixed Rate Nephelometry • Immunoturbidometric • Immunoassay (IA)

Testing Laboratory

N/A

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Monday - Friday; Report available: 4 - 7 days