17 Hydroxypregnenolone
Test Summary
17-Hydroxypregnenolone is useful in the diagnosis of 3-Beta-Hydroxylase enzyme deficiency, a rare cause of congenital adrenal hyperplasia, and 17-Hydroxylase (P450c17) enzyme deficiency.
Aliases
- N/A
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.4 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 5 days
- Frozen: 28 days
Limitations
Infants with 21-hydroxylase deficiency may present with non-elevated results.
Other Acceptable Specimens
N/A
Unacceptable Specimens
- Received room temperature
- Serum separator tube (SST)
- Gross hemolysis
- Grossly lipemic
- Grossly icteric
Order Code
17HYPR
EPIC (Premier) Code
LAB3666
Includes
N/A
CPT Code
- 84143
Billing Code
- 700000
CPT Statement
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Physician Attestation of Informed Consent
N/A
Testing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675
33608 Ortega Highway
San Juan Capistrano CA, 92675
Reference Range
| Adult Males | ≤700 ng/dL |
Adult Females, Pre-Menopausal
| Mid Follicular | 38-378 ng/dL |
| Surge | 33-583 ng/dL |
| Mid Luteal | 70-470 ng/dL |
Pediatric Male and Female
| <30 days | ≤3013 ng/dL |
| 1-11 months | ≤869 ng/dL |
| 1 year | ≤557 ng/dL |
| 2 years | ≤487 ng/dL |
| 3 years | ≤541 ng/dL |
| 4 years | ≤561 ng/dL |
| 5 years | ≤564 ng/dL |
| 6 years | ≤561 ng/dL |
| 7 years | ≤549 ng/dL |
| 8 years | ≤569 ng/dL |
| 9 years | ≤590 ng/dL |
| 10 years | ≤594 ng/dL |
| 11 years | ≤629 ng/dL |
| 12 years | ≤666 ng/dL |
| 13 years | ≤678 ng/dL |
| 14 years | ≤706 ng/dL |
| 15 years | ≤735 ng/dL |
| 16 years | ≤739 ng/dL |
| 17 years | ≤756 ng/dL |
Setup Schedule / Expected Turnaround Time
Sunday - Friday; Report available: 3 - 6 days
Specimen Collection
Special Instructions
N/A
Preferred Specimen
2 mL serum collected in a red-top tube (no gel)
Minimum Volume
0.4 mL
Instructions
N/A
Patient Preparation
N/A
Storage
N/A
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 24 hours
- Refrigerated: 5 days
- Frozen: 28 days
Limitations
Infants with 21-hydroxylase deficiency may present with non-elevated results.
Other Acceptable Specimens
N/A
Unacceptable Specimens
- Received room temperature
- Serum separator tube (SST)
- Gross hemolysis
- Grossly lipemic
- Grossly icteric
Result Information
Methodology
Chromatography/Mass Spectrometry
Testing Laboratory
N/A
Reference Range
| Adult Males | ≤700 ng/dL |
Adult Females, Pre-Menopausal
| Mid Follicular | 38-378 ng/dL |
| Surge | 33-583 ng/dL |
| Mid Luteal | 70-470 ng/dL |
Pediatric Male and Female
| <30 days | ≤3013 ng/dL |
| 1-11 months | ≤869 ng/dL |
| 1 year | ≤557 ng/dL |
| 2 years | ≤487 ng/dL |
| 3 years | ≤541 ng/dL |
| 4 years | ≤561 ng/dL |
| 5 years | ≤564 ng/dL |
| 6 years | ≤561 ng/dL |
| 7 years | ≤549 ng/dL |
| 8 years | ≤569 ng/dL |
| 9 years | ≤590 ng/dL |
| 10 years | ≤594 ng/dL |
| 11 years | ≤629 ng/dL |
| 12 years | ≤666 ng/dL |
| 13 years | ≤678 ng/dL |
| 14 years | ≤706 ng/dL |
| 15 years | ≤735 ng/dL |
| 16 years | ≤739 ng/dL |
| 17 years | ≤756 ng/dL |
Setup Schedule / Expected Turnaround Time
Sunday - Friday; Report available: 3 - 6 days