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Test Directory 11-Deoxycortisol

11-Deoxycortisol

Order Code: 11DEOX

Test Summary

11-Deoxycortisol (Compound S) is useful in diagnosing patients with 11-beta-hydroxylase deficiency (second leading cause of congenital adrenal hyperplasia) and primary (adrenal failure) or secondary (hypothalamic-pituitary ACTH deficiency) adrenal insufficiency.

Aliases

Compound S
Metyrapone Response

Specimen Collection

Special Instructions

N/A

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

Separate serum after clotting. An early morning specimen is preferred.

Patient Preparation

N/A

Storage

Plastic screw-cap vial

Transport Temperature

Frozen

Specimen Stability

Room Temperature = 72 hours
Refrigerated = 14 days
Frozen = 1 year

Limitations

N/A

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube, EDTA (royal blue-top) tube, or sodium heparin (green-top) tube

Unacceptable Specimens

N/A

Order Code

11DEOX

EPIC (Premier) Code

LAB3736

Includes

N/A

CPT Code

82634

Billing Code

670023

CPT Statement

Methodology

Chromatography/Mass Spectrometry

FDA Status

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Physician Attestation of Informed Consent

N/A

Testing Laboratory

Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano CA, 92675

Department

Reference Testing

Reference Range

See Laboratory Report

Setup Schedule / Expected Turnaround Time

Tuesday; Report available: 2 - 9 days